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Table 1.

Demographics of the study populations at the different types of test sites and for the different study populations.

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Fig 1.

Screenshots of the 6 assessments in the BrainCheck battery.

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Fig 2.

Normative data.

Each panel shows data from the indicated assessment. Only data from healthy individuals was used to create these histograms.

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Table 2.

Statistics of assessments included in the BrainCheck battery.

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Table 2 Expand

Fig 3.

Age dependence of the BrainCheck assessments.

For each battery, data shows the mean value of the indicated age ranges. Error bars indicate standard error of the mean, computed by bootstrapping.

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Fig 4.

Performance on BrainCheck assessments by (A) gender and (B) socioeconomic status. As explained in the text, assessments performed at different university test sites were used as a rough measure of the effect of socioeconomic status. Error bars represent standard error of the mean, computed by bootstrapping.

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Fig 5.

Test-retest reliability.

In all panels, each datapoint represents an individual who took the same assessment on two different dates. Black lines represent linear fits to the data. r-values for the fits are shown in the legend of each panel.

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Fig 6.

Individual metrics differ for concussed and healthy individuals.

For each assessment, normative histograms for healthy (blue) or concussed (red) individuals are shown.

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Table 3.

Performance of 30 mTBI patients compared to 30 orthopedic controls.

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Table 3 Expand

Fig 7.

Sensitivity and specificity of individual assessments.

For each assessment the sensitivity (true positive rate; red) and specificity (true negative rate; blue) are plotted as a function of the threshold for discriminating concussed from healthy individuals.

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Fig 8.

A composite score distinguishes concussed and healthy individuals.

(A) Distribution of the composite score for healthy (blue) and concussed (red) individuals. (B) Sensitivity (red) and specificity (blue) of a test based on the composite score plotted as a function of the threshold for identifying concussed individuals.

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Fig 9.

A test for malingering shows no dependence on cognitive performance.

(A) Screenshot of the malingering test. (B) Normative data for the test (C) Scores on the malingering test plotted by age. (D) Data for individuals who took the malingering test twice separated by at least one week. The score on the first trial is plotted against the score on the second. (E) Distribution of scores on the malingering test for healthy (blue) and concussed (red) individuals. (F) Specificity (blue) and sensitivity (red) of a test to distinguish concussed and healthy individuals based on the malingering test.

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