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Table 1.

Composition of hydrogels.

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Table 1 Expand

Fig 1.

Proposed reaction mechanism of Schiff base crosslinking of NSC and formation of semi-IPN through embedding of Poly (AAm-co-AA) in NSC network.

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Fig 1 Expand

Fig 2.

FTIR spectra of a) chitosan, b) NSC, c) Poly (AAm-co-AA), and d) SP2 hydrogel.

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Fig 2 Expand

Fig 3.

The NMR spectra of, a) 1H NMR of chitosan, b) 13C NMR of chitosan, c) 1H NMR of NSC, d) 13C NMR of NSC.

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Fig 3 Expand

Fig 4.

XRD spectra of the a) chitosan, b) NSC, and c) SP2 hydrogel.

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Fig 4 Expand

Fig 5.

TGA graphs of a) NSC and b) SP2 hydrogel.

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Fig 5 Expand

Fig 6.

Represent the surface morphology of a) SP1, b) SP2, c) SP3, d) SP7.

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Fig 6 Expand

Fig 7.

Swelling ratios of N-succinyl chitosan/ poly (AAm-co-AA) hydrogels at a) pH 7.4, b) pH 1.2.

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Fig 7 Expand

Table 2.

ESR at pH 1.2.

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Table 2 Expand

Table 3.

ESR at pH 7.4.

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Table 3 Expand

Table 4.

Diffusion parameters at pH 1.2/ pH 7.4.

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Table 4 Expand

Table 5.

Drug loading and encapsulation efficiency.

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Table 5 Expand

Fig 8.

Drug release at pH 1.2 and pH 7.4.

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Fig 8 Expand

Table 6.

Drug release kinetics at pH 1.2/ pH 7.4.

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Table 6 Expand