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Fig 1.

Study design flowchart.

ECG -electrocardiography, VO2 max—maximal oxygen consumption, FVC—forced vital capacity, FEV1—forced exhaled volume in the first second. During the whole study period (13 days), volunteers did not perform any exhaustive exercise besides those related to the study protocol.

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Fig 1 Expand

Table 1.

Parameters monitored during three repeated exhaustive treadmill exercise bouts separated by three days of resting period.

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Table 1 Expand

Table 2.

Blood cell count in eleven average-trained men before and after each of three bouts of exhaustive treadmill exercise.

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Table 2 Expand

Table 3.

Selected markers of muscle damage and metabolic response to exercise before and after each of three bouts of exhaustive treadmill exercise.

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Table 3 Expand

Fig 2.

Individual cf n-DNA responses to each of three repeated bouts of exhaustive treadmill exercise separated by three days of resting.

Eleven average-trained men executed three repeated treadmill exercise tests to exhaustion at speed corresponding to 70% of personal VO2 max and cf n-DNA was determined in pre- and post-exercise blood samples. The first studied men is marked by 1 and the last one is marked by 11. The same numbers at line segments represent responses of the same volunteer.

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Fig 2 Expand

Table 4.

Plasma concentrations of cell free nuclear (cf n-DNA) and mitochondrial (cf mt-DNA) DNA in eleven average-trained men before and after each of three bouts of exhaustive treadmill exercise.

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Table 5.

Percentage increments in circulating cell free nuclear and mitochondrial DNA and selected metabolic and muscle damage markers in response to three repeated bouts of exhaustive treadmill exercise in healthy average-trained men.

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Table 5 Expand