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Fig 1.

The causative lesion of TIO, as shown by MRI to identify the particular location.

1A. A 24-year-old female patient with tumor-induced osteomalacia has a lesion located in the right femoral head. The arrow represents the tumor area. 1B: Causative lesion located in the tibial plateau of a 51-year-old male tumor-induced osteomalacia patient. The white arrow represents the tumor area.

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Fig 1 Expand

Fig 2.

X-ray examination before and after joint arthroplasty in the treatment of tumor-induced osteomalacia patients.

2A: Osteoporosis and the causative lesion in a 52-year-old male TIO patient are shown on X-ray before joint arthroplasty. 2B: The patient underwent joint arthroplasty after one year. Osteoporosis was significantly improved, as shown by X-ray.

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Fig 2 Expand

Fig 3.

Pathological results of the patients.

Histopathological examination revealed that the neoplastic cells were spindled to stellate in shape with elaborate intrinsic microvasculature, infiltrating between bone trabecular (HE, 100x).

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Table 1.

Characteristics of TIO patients with joint arthroplasty.

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Table 1 Expand

Table 2.

The follow-up of arthroplasty with influence of TIO.

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Table 2 Expand

Fig 4.

Harris/KSS score for assessing joint arthroplasty before and one-year after surgery.

Thirteen patients underwent hip arthroplasty; changes in joint Harris score are shown in 4A. Three patients underwent knee arthroplasty; changes in joint KSS score are shown in 4B.

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Table 3.

Dynamic changes in bone metabolism indexes.

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Table 3 Expand