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Fig 1.

Flow diagram of the literature search and study selection for the meta-analysis.

The flow diagram shows eligible publications at each stage of the analysis process. The database search was conducted in December 2016.

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Table 1.

Characteristics of the studies included.

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Table 2.

Detection of the PD-L1 expression in TIICs in the selected studies.

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Fig 2.

Forest plot shows the associations between PD-L1 expression in TIICs and five year overall survival of cancer patients.

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Fig 3.

Subgroup analysis by different cutoff values shows the associations between PD-L1 expression in TIICs and five year overall survival of cancer patients.

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Fig 4.

Forest plot of hazard ratios shows the associations between PD-L1 expression in TIICs and cancer prognosis.

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Fig 5.

Forest plot of hazard ratios form subgroup analysis by different cutoff values shows the associations between PD-L1 expression in TIICs and cancer prognosis.

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Fig 6.

Forest plot of hazard ratios form subgroup analysis by different types of pathological sections shows the associations between PD-L1 expression in TIICs and cancer prognosis.

TMAs, tissue microarrays.

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Fig 7.

Forest plot of hazard ratios form subgroup analysis by different ethnicity shows the associations between PD-L1 expression in TIICs and cancer prognosis.

TMAs, tissue microarrays.

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Fig 8.

Begg’s funnel plots show the publication bias.

(A) Begg’s funnel plot for 5-years OS (B) Begg’s funnel plot for HR.

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