Fig 1.
Work flow of deciding the optimal number and locations of cutoff points.
Table 1.
Distribution of the patients’ baseline characteristics.
Table 2.
Optimal cutoff point: Total number of lymph node metastasis vs. survival.
Table 3.
Optimal cutoff point of tumor size against risk of lymph node metastasis.
Fig 2.
BMI distribution against hazard ratio (HR) in the event of death.
Arrow marks position of the lowest HR. BMI histogram is illustrated with bars at the bottom of the figure.
Table 4.
Multiple cutoff points: Body mass index (BMI) vs. death.
Fig 3.
Kaplan-Meier curves for the three risk groups of BMI using the validation cohort of 300 patients.
The log-rank test showed significant difference in risk of death between the groups (p = 0.028).
Fig 4.
Nomogram of survival probabilities with independent risk factors using the validation cohort of 300 patients.
Survival probabilities after 1 year through 5 years are calculated based on the effects of the three risk factors.
Table 5.
Multiple cutoff points: Depth of stromal invasion (in fraction) against risk of lymphovascular space invasion (LVSI).
Table 6.
Comparison of Findcut and X2: Stromal invasion vs. LVSI.