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Table 1.

Demographic characteristics and history of treatments of the patients with moderate to severe TAO.

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Table 2.

Clinical features of the patients with moderate to severe TAO.

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Table 2 Expand

Fig 1.

Examples of clinically active and inactive TAO.

(A) Moderate active TAO with lid retraction, inflammation of orbital soft tissue for both eyes. (B) Moderate inactive TAO with lid retraction. (C) Severe active TAO with severe binocular soft tissue inflammation, upper eyelid retraction and 25mm of Hertel reading for left eye. (D) Severe inactive TAO with lid retraction and 23mm of exophthalmos.

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Fig 1 Expand

Fig 2.

The age at diagnosis of patients with TAO.

(A) The bar diagram and (B) linear curves demonstrate the age at diagnosis (years) of patients with TAO.

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Fig 3.

Smoking status of the patients with TAO.

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Fig 4.

Temporal relationship between the diagnosis of TAO and thyroid dysfunction (hyperthyroidism or hypothyroidism).

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Table 3.

Comparison of exophthalmometric and asymmetric values between normal population and patients with moderate-to-severe TAO.

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Table 3 Expand

Fig 5.

Distribution of exophthalmometric value (worst eye) (A) and asymmetry of proptosis (B) for the patients with moderate-to-severe TAO.

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Fig 6.

Severe involvement of extraocular muscles on magnetic resonance imaging scan of a patient with TAO.

(A) Axial scan demonstrates the fusiform enlargement of extraocular muscles of a patient with thyroid associated ophthalmopathy (white arrows). (B) Coronal scan shows the involvement of muscle belly on magnetic resonance imaging scan of a patient with thyroid associated ophthalmopathy (white arrows).

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Fig 7.

Distribution of disease activity (A) and disease severity (B) in patients with TAO.

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Fig 7 Expand

Table 4.

Distribution of disease activity and severity in patients with moderate to severe TAO.

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Table 4 Expand