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Fig 1.

Flow chart.

NMBA: neuromuscular-blocking agent; RASS: Richmond Assessment Sedation Scale.

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Table 1.

Patient characteristics.

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Table 2.

Neurological assessment at the time of inclusion.

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Fig 2.

Representation of homogeneous and heterogeneous profiles.

The percentage of abolition of each tested neurological responses in homogeneous and heterogeneous profiles are depicted. The heterogeneous profile is characterized by a greater and more heterogeneous abolition of neurological responses.

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Table 3.

Latent class description and outcomes.

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Table 4.

Association between heterogeneous sub-phenotype and 28-day mortality.

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Fig 3.

28-day mortality probability according to the BRASS.

Mortality probability expressed in mean [95%CI], BRASS: Brainstem Responses Assessment Sedation Score.

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