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Table 1.

Comparison of the evaluated coding schema.

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Fig 1.

Weighted Venn diagrams of the distributions of power-enabled tests, replicated associations, best ORs, and best P values with CCS, ICD-9-CM, and phecodes.

Each color represents a resource.

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Table 2.

Results of tests for genetic replications on 440 SNP and phenotype pairs.

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Table 2 Expand

Fig 2.

PheWAS results of three SNPs (rs35391, rs731839 and rs769449) showed that phecodes outperformed ICD-9-CM and CCS.

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Fig 2 Expand

Fig 3.

PEPD expression results suggest strong association with the gastrointestinal tract.

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Fig 3 Expand

Fig 4.

SNP rs731839 is a cis acting eQTL for PEPD in esophagus mucosa.

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Fig 4 Expand