Table 1.
Primers used in T. pallidum strain typing.
Fig 1.
Patients selection flowchart.
Table 2.
Comparison of characteristics between serological cure and serofast status.
Fig 2.
Distribution of T. pallidum strains isolated from serofast patients and serological cure patients, 2011 to 2015.
The 14d/f type was the predominant subtype in two groups patients. The novel type of 14 i/a might predict an increasing risk of serofast status (χ2 = 34.4, P < 0.01).
Fig 3.
Serum levels of chemerin of early syphilis patient.
Detection serum levels of chemerin in control group (n = 30), early syphilis patients (n = 517), serological cure patients (n = 410) and serofast status patients (n = 104). The concentrations of chemerin were determined using a standard curve. Data are shown as the serum concentration of chemerin, and each bar represents the mean ± standard error. Unpaired t-tests was used to assess the significance of chemerin levels. The control group are healthy uninfected patients.
Fig 4.
The proportion of serofast patients by different time points RPR titre.
At different time points, the RPR titres in serofast patient changed. The proportion of patients with RPR titres of ≤1:8 increased from 64.4% at baseline to 98.0% at 12 months.
Table 3.
Multivariate analysis of factors associated with serofast patients.