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Fig 1.

Flow chart of study inclusion process.

ED, Emergency Department; BMI, Body Mass Index *Patients connected to either AG 110 system or subglottic suction system after 6 hours from tracheal intubation **The reasons for excluding patients at admission were: suspicion of pneumonia and lung contusion on chest X ray (n = 375); mechanical ventilation during previous three months (n = 58); facial, oropharingeal and neck trauma (n = 123); difficult intubation (n = 28); BMI >40 (n = 16).

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Table 1.

Baseline patient characteristics.

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Table 2.

Outcome measures in the Anapnoguard 100 and control groups.

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Fig 2.

Comparison between AG group and control group according to total SS drained.

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Fig 3.

Comparison between AG group and control group according to daily SS drained.

AG, Anapnoguard; Pcuff, Cuff Pressure; SS, Subglottic Secretions.

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Fig 4.

Cumulative rates of patients remaining free of VAP in the AG group and control group, using the Kaplan-Meier method.

VAP, Ventilator-Associated Pneumonia; AG, Anapnoguard.

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Fig 5.

AnapnoGuard 100 system overview.

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Fig 6.

Automatic endotracheal tube cuff pressure closed loop adjustment.

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Fig 7.

Subglottic secretions drainage based on rinsing and suctioning.

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