Fig 1.
Reaction of 2-aminoquinolin-4(1H)-one with primary and secondary amines.
Fig 2.
Plausible mechanism of the reaction yielding tetrahydropyrimido[4,5-b]quinolin-5-ones 5.
Fig 3.
Plausible mechanism of the reaction yielding pyrimido[4,5-b]quinolin-3-ium salt 4.
Fig 4.
Transformation of 2-aminoquinolin-4(1H)-one and Mannich products 2 to bis and tris-quinolinone derivatives.
Fig 5.
Plausible mechanism leading to derivatives 3 and 6.
Fig 6.
Reaction of Mannich product 2a with indole and thiophenol.
Fig 7.
ORTEP view of compounds 2b and 5a.
Displacement ellipsoids are drawn at the 50% probability level.