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Table 1.

Baseline demographic and clinical characteristics of study sample.

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Fig 1.

Flowchart of patient selection.

Fig 1 presents the distribution of patients after imputing the missing values. The labels on the arrows indicate the number of years of follow-up required in the training dataset and which filters were applied. The first box indicates the total number of patients assessed. Note that P (and %P) refers to the number (and percentage) of patients who meet “progression” criteria within the different subgroups.

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Table 2.

Predictors of disease classification.

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Table 3.

Predictive accuracy for different groups using 12 month visit without MRI based on ten-fold cross-validation.

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Table 4.

Predictive accuracy for different groups using 12 month visit with MRI based on ten-fold cross-validation.

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Table 5.

Predictive accuracy for different groups using 24 month visit without MRI based on ten-fold cross-validation.

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Table 6.

Predictive accuracy for different groups using 24 month visit data with MRI based on ten-fold cross-validation.

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Table 7.

Comparison of predictive accuracy for Group 2 (G2) using 12 month and 24 month clinical and MRI data based on ten-fold cross-validation.

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