Table 1.
General demography of methadone maintenance treatment patients.
Fig 1.
A schematic design from a pharmacogenomic study in methadone maintenance therapy.
This design has led to systemic discovery of some hidden pathways among plasma IL-7, ADAM10 and CDH2, and their contributions to the methadone treatment responses.
Table 2.
Association analyses between SNPs in CDH2 gene and blood pressure or plasma level of CDH2.
Fig 2.
Correlation matrix heatmap of the study variables.
Spearman correlation coefficients are presented by a blue-white-red color scheme. Dark red indicates a more positive correlation; dark blue indicates a more negative correlation; white indicates no correlation.
Table 3.
Multivariate regression analyses of the plasma CDH2 level (ng/ml).
Table 4.
Plasma level of CDH2 and IL-7 were associated with HIV infection status and the urine morphine test outcome.