Table 1.
Patient characteristic.
Fig 1.
Boxplots of relative apparent diffusion coefficient (rADC) from patients with progressive disease (PD) and pseudoprogression (PsP).
Boxplots showing the percentage of voxels with a decrease of rADC ≥ 0.25 between baseline and follow-up rADC values for patients with PD (n = 28) and PsP (n = 7). The percentage of rADC is higher in patients with PD (59.2%; Q1 36.7; Q3 78.6) than in those with PsP (18.6%; Q1 3.04; Q3 26.5) (p = 0.005).
Fig 2.
Analysis of a 49-year-old male patient with progressive disease (PD).
Contrast enhanced T1w MR images (A-B). Follow-up image with delineated tumor region of interest (ROI) (A). Parametric response map of relative apparent diffusion coefficient (rADC) (B). The resulting quantitave scatter plot (C). The voxels are color-coded corresponding to their changes between baseline and follow-up examinations. Blue is designated to voxels with a decrease of rADC ≥ 0.25, red to an increase of rACD < 0.25 and green to changes in between these thresholds.
Fig 3.
Analysis of a 38-year-old female patient with pseudoprogression (PsP).
Contrast enhanced T1w MR images (A-B). Follow-up image with delineated tumor region of interest (ROI) (A). Parametric response map of relative apparent diffusion coefficient (rADC) (B). The resulting quantitave scatter plot (C). The voxels are color-coded corresponding to their changes between baseline and follow-up examinations. Blue is designated to voxels with a decrease of rADC ≥ 0.25, red to an increase of rACD < 0.25 and green to changes in between these thresholds.