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Table 1.

Demographic and clinical characters for the BD, MDD and the Control group.

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Fig 1.

Regions showing significant differences in fALFF between each of the two groups.

(A) demonstrates regions showing group difference between the BD and CON groups, with the fALFF value increased in BD relative to the controls. (B) demonstrates the region exhibiting group difference between the MDD and CON group, with the fALFF value increased in the CON group relative to MDD.(C) demonstrates regions showing group difference between the BD and MDD groups, with the fALFF value increased in BD relative to MDD. The color bar means the intensity of Z-value, yellow/red in the color bar denotes relatively higher fALFF values, and cyan /blue in the color bar denotes relatively higher fALFF values. Locations of the clusters showing group differences were indicated by Arabic numbers labeled in each image. The number in the lower right corner of each image refers to the z MNI coordinates. Brain region labels: 1. left putamen; 2. right putamen; 3. left superior frontal gyrus/medial frontal gyrus; 4. right putamen; 5. left putamen; 6. left superior frontal gyrus. Left in the figure indicates the right side of the brain. BD: bipolar disorder. MDD: major depression. CON: control.

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Table 2.

Regions showing significant differences in fALFF among the groups.

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Fig 2.

Comparisons of mean fALFF value in each ROI across groups generated from post hoc analysis using Bonferroni correction.

Distinct ROIs were presented in the X-axis. The Y-axis represented mean fALFF value of each ROI. A single asterisks means a significance level of p < 0.05, and double asterisks indicate a significance level of p <0.01. BD: bipolar disorder. MDD:. CON: control. L PUT BD-CON: left putamen resulted from BD vs. CON comparison; R PUT BD-CON: right putamen resulted from BD vs. CON comparison; L SFG MDD-CON: left SFG/medial frontal gyrus resulted from MDD vs. CON comparison; R PUT BD-MDD: right putamen resulted from BD vs. MDD comparison; L PUT BD-MDD: left putamen resulted from BD vs. MDD comparison; L SFG BD-MDD: left SFG resulted from BD vs. MDD comparison.

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