Fig 1.
Multifactorial causes of abdominal symptoms in CF.
CFLD–CF-associated liver disease, CFRD–CF-related diabetes, DIOS–distal intestinal obstruction syndrome, GERD–gastroesophageal reflux disease, MI–meconium ileus, PI–pancreatic insufficiency.
Fig 2.
Pain and non-pain symptoms of the JenAbdomen-CF Score 1.0.
*to some extend additionally related to pain symptoms.
Table 1.
Patient characteristics.
Fig 3.
Abdominal symptoms in patients with CF.
Frequencies of abdominal symptoms in CF patients of all ages (Fig 3a) and in children compared with adults (Fig 3b). N.d.–not determined (missing data).
Table 2.
Frequency of abdominal symptoms in patients with CF.
Fig 4.
Location of abdominal pain in patients with CF.
Table 3.
Abdominal pain characteristics.
Fig 5.
JenAbdomen-CF Score 1.0 of patients presenting indicated abdominal manifestations and complications of surgery in comparison with patients without history of these events (Ø).
Int PsA–intermittently colonized with P. aeruginosa, chr PsA–chronically colonized with P. aeruginosa. Means ± SEM.
Fig 6.
JenAbdomen-CF Score 1.0 in relation to genotype.
Left: Scores obtained from `mild´ (PIP≤0.25) compared to `moderate-severe´ (PIP>0.25) genotypes. Right: Scores of patients carrying the G551D mutation compared to those without this mutation. Of note, the fact that 10/17 of the patients with G551D mutation received ivacaftor may have influenced the result.