Table 1.
Demographics for all decedents for whom a VA was conducted, stratified by parent study (n = 259).
Table 2.
Numbers and resultant CSMFs generated for grouped ICD-10 and study-defined CoD categories in those with autopsy data available, as assigned by the clinicopathological panel, PCVA, InterVA-4, and SmartVA-Analyze (n = 34).
Table 3.
Summary of measures of performance of PCVA, InterVA-4, and SmartVA-Analyze in assigning CoD in ICD-10 or study-defined categories, compared to L3 (n = 34) and L2 (n = 259) reference standards.
Fig 1.
Alluvial* diagram showing CoD† as assigned by the clinicopathological panel (left) and PCVA (right); n = 34 [36].
*Each horizontal band represents one decedent. †Combined ‘immediate’ and ‘underlying’ ICD-10 CoD. ‡Comparison based on study-defined codes. AIDS: acquired immune deficiency syndrome; CCC: chance-corrected concordance; CMV: cytomegalovirus; CNS: central nervous system; CoD: cause of death; HIV: human immunodeficiency virus; K: Cohen’s kappa; L3: level three (using operational, research, and autopsy data); NCD: non-communicable diseases; NTM: non-tuberculous mycobacteria; PCP: Pneumocystis pneumonia; PCVA: physician-certified verbal autopsy; TB: tuberculosis.
Fig 2.
Alluvial* diagram showing CoD as assigned by clinicopathological panel† (centre), InterVA-4‡ (left) and SmartVA-Analyze (right); n = 34 [36].
*Each horizontal band represents one decedent. †Combined ‘immediate’ and ‘underlying’ ICD-10 CoD. ‡InterVA-4 CoD with highest associated likelihood. AIDS: acquired immune deficiency syndrome; CCC: chance-corrected concordance; CMV: cytomegalovirus; CNS: central nervous system; CoD: cause of death; HIV: human immunodeficiency virus; K: Cohen’s kappa; L3: level three (using operational, research, and autopsy data); NCD: non-communicable diseases; NTM: non-tuberculous mycobacteria; PCP: Pneumocystis pneumonia; PCVA: physician-certified verbal autopsy; TB: tuberculosis.
Table 4.
Numbers and resultant CSMFs generated for grouped ICD-10 and study-defined CoD categories, as assigned by L2 and L1 clinical panels, PCVA, InterVA-4, and SmartVA-Analyze (n = 259).
Table 5.
Sensitivity, specificity, and chance-corrected concordance of PCVA, InterVA-4, and SmartVA-Analyze in the detection of specific CoD compared to L3 (n = 34) and L2 (n = 259) clinical reference standards.