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Fig 1.

CONSORT flow diagram.

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Table 1.

Demographic data and neuropsychiatric profiles (full analysis set).

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Table 2.

No change of apathy, irritability, cognition or function after 10 weeks of treatment with bupropion.

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Table 2 Expand

Table 3.

Change of apathy after the first treatment period suggests activation through trial participation.

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Table 3 Expand