Fig 1.
Participant flow diagram and study selection process.
Table 1.
Baseline characteristics of patients.
Table 2.
Adjusted odds ratios for association between predictors of incidences of composite cardiovascular events (final step of predictor selection).
Fig 2.
Comparison discrimination ability of new risk model with Framingham model by gender.
Results described are c-statistics. (A) The comparison between the new model and Framingham model in men (n = 2,224). (B) The comparison in women (n = 1,372). Circles indicate the AUC of the new model, and triangles indicate that of the FRS model.
Fig 3.
Calibration plot for new model.
Result shows the consistency between predicted CV events by new model and observed CV events using a calibration plot. The dotted line indicates perfect fitting, and the solid line indicates the predicted probabilities.
Fig 4.
Risk score and incidence of observed CV events in each model.
Results shows the association between the risk score and observed CV events. Scores were four groups based on risk score quartile (Grade 1 to 4). Fig 4A shows Framingham risk score by gender. Fig 4B shows new risk score.