Type 2 porcine reproductive and respiratory syndrome virus infection increases apoptosis at the maternal-fetal interface in late gestation pregnant gilts | PLOS One

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Fig 1 — Fig 1.

TUNEL assay in the uterine-fetal placental tissues from PRRSV-infected pregnant gilts.
(A) Focal area of apoptosis (arrow) affecting both the trophoblast and uterine epithelial cells at the uterus-fetal placenta interface from PRRSV-infected pregnant gilt. (B) Multiple apoptotic cells (arrows) closely associated with the area of microseparation between chorioallantois and uterus (asterisk) from PRRSV-infected gilt. (C) Apoptotic uterine luminal epithelial and trophoblastic cells in the area of severe separation of the chorioallantois from the uterus (arrow). (D) Single cell apoptosis of inflammatory cells in the endometrium (arrow); endometrial artery with the apoptotic endothelial cell (arrowhead).

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Fig 2 — Fig 2.

Mean numbers of TUNEL (apoptotic) positive cells per 1 mm² of the endometrium and maternal-fetal interface.
Superscript letters (^{a, b, c} or ^{d, e, f}) indicate significant differences (P < 0.05) between PRRSV viral load groups. Error bars represent standard deviation.

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