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Table 1.

Key concepts in current North-American clinical practice guidelines for diagnosis of streptococcal pharyngitis, with corresponding quotes.

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Fig 1.

Model-based selective testing strategy.

Abbreviations: GAS, group A streptococcus.

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Table 2.

Predictor variables included in the multivariable model.

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Table 2 Expand

Fig 2.

Calibration plot of calculated probabilities of group A streptococcus (GAS) and observed outcomes (N = 676).

Circles represent mean calculated probabilities versus observed proportions in subgroups defined by quintiles of the calculated GAS probabilities (m = 1). Vertical bars are 95% confidence intervals. Dashed diagonal line represents perfect calibration.

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Fig 2 Expand

Fig 3.

Distribution of calculated probabilities of group A streptococcus (GAS) when applying the clinical prediction model.

The vertical dashed lines represent thresholds used to define low and high probability of GAS (calculated probability of GAS<0.12 and >0.85, respectively). The vertical black line represents disease prevalence (0.41).

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