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Fig 1.

Method flowcharts.

(a) Palpation in a tele-manipulation environment; (b) Palpation in a data-driven virtual tissue model. Haptic device Geomagic Touch is used to control the position; Fanuc robot follows the trajectory; force sensing probe scans the silicone phantom; virtual tissue displays on a computer monitor; probe position is displayed in real time; stiffness distribution color map is generated using force and indentation depth data.

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Fig 2.

Schematic of the experimental haptic manipulator.

The right column shows the slave-side hardware: a camera, a robot arm, a sliding indentation probe, and a silicone phantom tissue. The left column shows the master-side configuration: a live camera image, a visual stiffness display, and force feedback via a haptic device. The middle column lists the software.

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Fig 3.

Tele-operation architecture.

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Fig 4.

Hermite curve interpolation trajectory generation.

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Fig 5.

Position response.

(a) when no force feedback is applied and (b) when force feedback is applied.

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Fig 6.

(a) Mapping stiffness data to RGB value and (b) stiffness map generation.

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Fig 7.

Silicone soft-tissue phantom.

(a) the locations of the 3 embedded nodules are highlighted (A, B, C); (b) an operator remotely palpated the phantom tissue by using the same trajectory, which covers nodules A and B, guided by the two black tags.

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Fig 8.

Stiffness map estimated from the perpendicular reaction force along the same trajectory in multiple trials of remote palpation with increased velocity from trials 1 to 7.

Nodules A and B are presented in red or orange, whereas other areas are presented in blue or cyan.

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Table 1.

Overview of participant demographics and experience in the palpation experiment with the tele-operation system (Experiment II).

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Fig 9.

Two stiffness maps generated during 2 trials by visual stiffness feedback.

The upper maps show the orientations of the artificial organ, whereas the lower maps show the corresponding stiffness.

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Fig 10.

Nodule detection results.

(a) Nodule detection sensitivities of visual stiffness feedback and force feedback and Wilson score intervals at a 95% confidence level; (b) Detection sensitivities of each nodule and Wilson score intervals at a 95% confidence level; (c) Time elapsed to determine nodule locations by visual stiffness feedback and force feedback in a tele-manipulation environment: data were averaged over all 10 subjects, and standard error bars are shown (The standard error of the mean is the standard deviation of the sampling distribution of a statistic [34]; it is an indicator of result precision).

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Fig 11.

User interfaces of the nodule size discrimination experiment.

The buried nodule is marked using black hollow squares; the orientation of the phantom tissue is changed for each trial.

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Table 2.

Overview of participant demographics and experience in the virtual palpation experiment (Experiment III).

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Fig 12.

Results of nodule size discrimination.

(a) Overall discrimination rates of nodule sizes by the two stiffness feedback modes and their Wilson score intervals at a 95% confidence level; (b) Discrimination rates of the nodule sizes of each nodule pair and their Wilson score intervals at a 95% confidence level.

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