Fig 1.
Study flow chart.
Fig 2.
General diagnostic work up and identification of patients with an isolated pocket infection.
Fig 3.
Selection and description of the 14 analysed biomarkers.
Table 1.
Detailed overview of applied assays for biomarker-analysis.
Table 2.
Characteristics of 25 patients with isolated cardiac device pocket infection and 50 control patients.
Table 3.
Comparison of biomarker levels between infected and control groups using established cut-offs.
Fig 4.
Comparison of biomarker levels between infected and control groups using absolute concentration.
Fig 5.
Receiver operator characteristic curve (ROC)-Analysis for the relevant biomarkers.
Table 4.
Comparison of sensitivity and specificity for relevant biomarkers applying established or optimized cut-off values.