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Fig 1.

Flow chart of study selection process.

PRISMA flow chart of the selection process of SMT-treated FD. SMT = Si-Mo-Tang oral liquid, FD = functional dyspepsia.

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Table 1.

Summary of the characteristics of the included studies.

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Table 1 Expand

Fig 2.

The risk of bias assessment with the Cochrane Collaboration tool.

(A)Risk of bias graph. (B)Risk of bias summary.

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Fig 2 Expand

Fig 3.

Efficacy rate and publication bias of SMT-treated FD after subgroup of SMT alone or combine with WM versus placebo or WM and sensitivity analysis.

(A)Forest plot of comparison: the efficacy rate of symptoms. (B) Funnel plot of publication bias of the included studies. SMT = Si-Mo-Tang oral liquid, WM = western medicine, FD = functional dyspepsia.

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Fig 3 Expand

Fig 4.

Forest plot of the efficacy rate of SMT-treated FD after subgroup analysis of the different kinds of control interventions among SMT versus WM.

SMT = Si-Mo-Tang oral liquid, WM = western medicine, FD = functional dyspepsia.

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Fig 4 Expand

Fig 5.

Forest plot of the efficacy rate of SMT-treated FD after excluding poor quality studies.

SMT = Si-Mo-Tang oral liquid, WM = western medicine, FD = functional dyspepsia.

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Fig 5 Expand

Fig 6.

Forest plot of relapse rate of SMT-treated FD between experimental and control group.

SMT = Si-Mo-Tang oral liquid, FD = functional dyspepsia.

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Fig 6 Expand

Fig 7.

Forest plot of safety profile and adverse events of SMT-treated FD.

SMT = Si-Mo-Tang oral liquid, FD = functional dyspepsia.

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Fig 7 Expand