Fig 1.
Representative scanning electron microscopy image of FA-SLN.
The particle size of the depicted particles is in the range of 100 to 130 nm.
Fig 2.
Representative intensity and number based particle size distributions of blank SLN, FA-SLN and Toc-SLN at times zero, 6 weeks and 15 weeks.
Table 1.
Z-average, polydispersity index (PdI) and zeta potential of SLN directly after preparation and after 6 and 15 weeks of storage, n = 3.
Table 2.
Recovery of FA and Toc from SLN directly after preparation and after 15 weeks of storage, n = 3.
Fig 3.
Encapsulation efficiency of FA and Toc in SLN.
A) Encapsulated absolute amounts and B) encapsulation rates. Total concentrations on the x-axis refer to the extracted amounts of FA or Toc. The dataset is available in S1 Dataset.
Fig 4.
Radical scavenging activity of FA-SLN (A) and Toc-SLN (B).
Samples were analyzsed directly after preparation, 6 weeks and 15 weeks of storage. SLN were diluted 40-fold resulting in antioxidant concentrations given on the x-axis. The dataset is available in S2 Dataset.
Fig 5.
XRD patterns of blank SLN, FA-SLN and Toc-SLN.
Peaks were assigned to modifications typically described in the literature. XRD patterns were scaled to the intensity of the first peak.
Fig 6.
Representative melting curves of loaded and unloaded SLN.
Samples were analysed directly after preparation and after 15 weeks of storage recorded applying heating rates of 1 K min−1 or 10 K min−1. FA or Toc contents in the SLN were 2.8 mg g−1. Vertical lines at 50°C and 56°C serve as guides to the eye.
Fig 7.
Proportions of peak 1, peak 2 and peak 3 in melting curves of SLN containing different amounts of FA (A-C) or Toc (D-F).
The dataset is available in S3 Dataset.