Table 1.
Schizophrenia-associated SNPs with a p-value of <0.05 in our bipolar disorder GWAS data after correction for sample overlap.
Fig 1.
Results of the Ingenuity Pathway Analysis.
Results of the Ingenuity Pathway Analysis (IPA) are shown in bar plot format. The x-axis shows negative logarithmic enrichment p-values for all associated pathways containing two and more genes prior to- (gray) and after- (blue) Benjamini Hochberg correction for multiple testing. The red horizontal line indicates a p-value of 0.05.
Fig 2.
IPA pathway synaptic long term potentiation.
Results of the Ingenuity pathway analysis (IPA) for the pathway “Synaptic Long Term Potentiation” are shown. Shared schizophrenia-bipolar disorder associated genes (GRIN2A, GRM3, CACNA1C) are highlighted in purple.
Fig 3.
Results of the INRICH pathway analysis.
Results of the INRICH pathway analysis are shown in bar plot format. The x-axis shows negative logarithmic enrichment p-values for all nominally associated pathways containing two and more genes prior to- (gray) and after- (blue) correction for multiple testing. The red horizontal line indicates a p-value of 0.05.