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Fig 1.

Flow diagram of patient enrollment and endoscopic procedure.

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Fig 2.

Appearance of the GIM with the lens closing to the lesions.

A, the lesion shows bluish-whitish areas with a regular mucosal pattern in the NBI model. B, the lesion shows whitish patches with a regular mucosal pattern in the AA-NBI model.

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Fig 2 Expand

Table 1.

The demographics of the study samples.

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Table 1 Expand

Table 2.

Clinical characteristics of the study samples.

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Table 2 Expand

Fig 3.

Appearance of intestinal metaplasia in the antrum of the same patient under three different endoscopic models.

A, Endoscopic image in WLE shows ash-colored nodular changes. B, After being switched to the NBI model, the lesions exhibit as bluish-whitish areas. C, The clearer whitish patches are observed after sprinkling with acetic acid in the AA-NBI model. D, Targeted biopsy shows intestinal metaplasia of the stomach.

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Fig 3 Expand

Fig 4.

Appearance of intestinal metaplasia in the antrum of the same patient under three different endoscopic models.

A, Endoscopic image in WLE shows antrum mucosa is normal. B, After being switched to the NBI model, bluish-whitish areas appear. C, The clearer whitish patches are observed after sprinkling with acetic acid in the AA-NBI model. D, Targeted biopsy shows intestinal metaplasia of the stomach.

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Fig 4 Expand

Fig 5.

Appearance of intestinal metaplasia in the antrum of the same patient under three different endoscopic models.

A, Endoscopic image in WLE shows antrum mucosa is normal. B, After being switched to the NBI model, no obvious bluish-whitish areas appear. C, The whitish patches are observed after sprinkling with acetic acid in the AA-NBI model. D, Targeted biopsy shows intestinal metaplasia of the stomach.

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Fig 5 Expand

Table 3.

Patients with histologically confirmed diagnosis of GIM.

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Table 3 Expand

Table 4.

Diagnostic accuracy of endoscopy in patients with GIM by WLE, NBI and AA-NBI.

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