Fig 1.
Relative expression of Tnmd and Scx mRNA in Achilles tendons.
(a Scx and (b Tnmd gene expression in intact and ruptured Achilles tendons of Wistar and diabetic GK rats at day 14 post-rupture. Results are expressed as mean ± SEM with n = 4 in Wistar groups and n = 4 in diabetic GK groups (ANOVA followed by Fisher’s protected least significant difference test).
Fig 2.
Relative expression of Ngf, Bdnf, Tsp1, Nk1, Trka and Trkb mRNA in the Achilles tendons.
a) Relative gene expression of Ngf b) Bdnf, c) Tsp1, d) Nk1, e) Trka and f) Trkb in the intact and ruptured Achilles tendons of Wistar and diabetic GK rats at day 14 post-rupture. Results are expressed as mean ± SEM with n = 4 in Wistar groups and n = 5 in diabetic GK groups. *P ≤ 0.05, **P ≤ 0.005 and ***P ≤ 0.0005 compared to intact and ruptures Wistar and #P ≤ 0.05 compared to intact GK group (ANOVA followed by Fisher’s protected least significant difference test).
Fig 3.
NGF, BDNF and TSP1 expression in Achilles tendon.
Expression of NGF, BDNF and TSP1 in intact and ruptured tendon of Wistar and diabetic GK rats at day 14 post-rupture. Original magnification is 20x; bars = 100 μm. (I; Intact part of the tendon and R; Ruptured area).
Fig 4.
NK1 and Trk expression in Achilles tendon.
Expression of NK1 and Trk in intact and ruptured tendon of Wistar and diabetic GK rats at day 14 post-rupture. Original magnification is 20x; bars = 100 μm. (I; Intact part of the tendon and R; Ruptured area).