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Fig 1.

Study sample (flow diagram).

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Table 1.

Baseline characteristics and disease activity of patients in the study population according to treatment.

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Table 2.

Utility gain and effectiveness of different biologics at 6 months follow-up.

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Table 2 Expand

Fig 2.

Drug survival, stratified by drug.

The graph for the Kaplan-Meier estimated survival has been censored when the number at risk was below 10. The number of patients on a drug at different time points is listed below the figure.

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Fig 2 Expand

Fig 3.

Drug survival, stratified by anti-TNF naive, anti-TNF switchers and other modes of action switchers (OMA switchers) in biologic monotherapy.

The graph for the Kaplan-Meier estimated survival has been censored when the number at risk was below 10. The number of patients on a drug at different time points is listed below the figure.

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Fig 3 Expand

Fig 4.

Drug survival, stratified by 1st, 2nd and 3rd line biologic monotherapy.

The graph for the Kaplan-Meier estimated survival has been censored when the number at risk was below 10. The number of patients on a drug at different time points is listed below the figure.

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Fig 4 Expand

Table 3.

Utility gain and effectiveness of anti-TNF naïve, anti-TNF switchers and other modes of action (OMA) bDMARDs 6 months follow-up.

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Table 3 Expand