Table 1.
Patient demographic data (n = 187) and summary of six optic disc parameters.
Fig 1.
The canonical plot that are used to discriminate various optic disc appearances by the discriminant formulas.
The biplot axes are the first two canonical variables that provide maximal separation among the groups. A plus (+) marker corresponds to the multivariate mean of each group. A circle around the plus marker corresponds to a 95% confidence ellipse for each mean. If two groups differ significantly, the confidence ellipses tend to not intersect. The labeled rays show the directions of the covariates in the canonical space. pFI, predicted focal ischemic; pGE, predicted generalized enlargement; pMY, predicted myopic glaucomatous; and pSS, predicted senile sclerotic.
Fig 2.
The receiver operating characteristic curves that are used to predict optic disc appearances by the discriminant formulas.
pFI, predicted focal ischemic; pGE, predicted generalized enlargement; pMY, predicted myopic glaucomatous; pSS, predicted senile sclerotic; and AUC, area under the receiver operating characteristic curves.
Table 2.
Comparisons of six optic disc parameters among four optic disc types predicted by the Glaucoma Stereo Analysis Study classification.
Table 3.
Comparisons of various demographic parameters among four optic disc types predicted by the Glaucoma Stereo Analysis Study classification.
Fig 3.
The representative optic discs have various mixing rates.
The color fundus photographs (A, B, C), image analysis results (D, E, F), and depth maps in the horizontal meridian (G, H, I) from cases 1 (A, D, G), 2 (B, E, H), and 3 (C, F, H) are shown. Based on the discrimination formulas, cases 1, 2, and 3 are predicted to have 62% probability of GE elements, 48% and 35% probabilities of MY and FI elements, respectively, and 31%, 20%, 28%, and 21% probabilities of FI, GE, MY, and SS elements, respectively. Based on the definitions described in the Methods, cases 1, 2, and 3 are classified as having single, mixed, and unclassifiable types of optic discs, respectively.
Table 4.
Distributions of single, mixed, and unclassifiable types of optic disc appearances among subjects.