Table 1.
Cell lines used in the study.
Table 2.
Cell line quality and tumorigenicity parameters.
Fig 1.
Soft agar colony assay results.
Representative captures of in vitro transformation assay results are reported for each investigated cell line.
Fig 2.
Tumorigenic evaluation and histology.
Representative captures of the absence (A) and presence (B) of a nodular lesion, localized at the site of injection of cells, in treated nude mice. In Panel C histological sections derived from cell-treated mice are reported.
Fig 3.
Susceptibility of cell lines to Poliovirus.
Attenuated Poliovirus Sabin LsC 2ab Sabin type 1 (Panel A), P712 Ch 2ab Sabin type 2 (B) and Leon 12alb Sabin type 3 (C) infectious titers obtained on the indicated cell lines. Data are reported as TCID50/ml log10 mean ± standard error of the mean. Asterisk indicates a P value < 0.05 significance between the two data sets marked by the line.