Table 1.
PICOS criteria for eligibility of studies.
Fig 1.
Flowchart of literature search.
Table 2.
Characteristics of studies included in the systematic review of PPV23 efficacy/effectiveness.
Fig 2.
Forest plots of meta-analyses of randomized controlled trials, outcomes IPD and pneumococcal pneumonia.
IPD = invasive pneumococcal disease
PP = pneumococcal pneumonia
RCT = randomized controlled trial.
Fig 3.
Forest plots of meta-analyses of observational studies, outcome IPD.
IPD = invasive pneumococcal disease
VT-IPD = vaccine-serotype IPD.
Fig 4.
Forest plots of meta-analyses of observational studies, outcome pneumococcal pneumonia.
PP = pneumococcal pneumonia.
Table 3.
Overview of recent meta-analyses of PPV23 efficacy/effectiveness.