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Fig 1.

Overview of exposure and follow-up.

Exposure was recorded as the change in body weight between two subsequent surveys. Subjects were followed until the date of a third survey or December 31, 2012. Subjects who attended three or more subsequent surveys thus contributed with multiple exposures and follow-up periods.

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Fig 1 Expand

Fig 2.

Distribution of weight change (in kgs) in the study population

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Fig 2 Expand

Table 1.

Baseline Characteristics of the Study Population Across Categories of Weight Change

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Table 1 Expand

Table 2.

Incidence Rates (IR) and Hazard Ratios (HR) with 95% Confidence Intervals (CI) for Venous Thromboembolism (VTE) According to Changes in Body Weight, Stratified by BMI at the Start of the Weight Change Interval

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Table 2 Expand

Fig 3.

Hazard Ratios for Venous Thromboembolism According to Changes in Body Weight and Body Mass Index Measured at the Start of the Weight Change Interval.

Subjects with BMI <25 kg/m2 and 0–7.4 kg weight gain were used as reference. Age as time-scale, adjusted for sex.

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Fig 3 Expand

Table 3.

Crude Incidence Rates (IR) and Hazard Ratios (HR) with 95% Confidence Intervals (CI) for Provoked and Unprovoked Venous Thromboembolism (VTE) According to Changes in Body Weight.

Stratified According to BMI at the start of the weight change interval.

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Table 3 Expand

Table 4.

Hazard Ratios (HR) with 95% Confidence Intervals (CI) for Provoked and Unprovoked Venous Thromboembolism According to Changes in Body Weight, Competing Risk by Cancer and Competing risk by Death Analysis

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Table 4 Expand