Fig 1.
Boxplots of measured cytokine concentrations.
Fig 2.
Scatterplots of p16INK4a expression versus cytokine concentrations.
Observations with quantifiable cytokine concentrations are displayed as blue circles; concentrations below the LLQ are displayed as red + symbols. Cytokine concentrations and p16INK4a expression were natural-log transformed and log2 transformed, respectively. A descriptive LOESS curve is plotted handling below LLQ values as observed. Correlation estimates were less than or equal to 0.22 for all associations (Table 1). LLQ, lower limit of quantification.
Table 1.
Correlation between natural-log transformed cytokines and log2 transformed p16INK4a expression.
Table 2.
Elastic net results for TFV-dp AUC, FTC-tp AUC, dATP AUC, and dCTP AUC