Fig 1.
Flow chart of patients we analyzed in the present study.
PCI: percutaneous coronary intervention, OGTT: oral glucose tolerance test, DM: diabetes mellitus, OCT: optical coherence tomography, and IVUS: intravascular ultra sound.
Table 1.
Clinical characteristics of the study population.
Table 2.
Clinical characteristics of the study population on optical coherence tomography.
Fig 2.
Representative cross-sectional OCT images for each of the 3 groups, NGT, IGT and DM (A, B, and C, respectively).
We measured the thickness of the thinnest part (arrows) of the fibrous cap identified as a signal-rich homogenous region overlying a lipid core (*), which is characterized by a signal-poor region.
Fig 3.
Comparisons of OCT findings of coronary plaques containing lipid core between NGT, IGT, and DM groups.
Maximum and mean lipid arc (panels A and B) and thickness of fibrous cap (panel C). Data are expressed as mean ± SD.
Fig 4.
Relationships between OCT findings (maximum lipid arc and fibrous cap thickness) and LDL-C (panels A and B), HDL-C (panels C and D) and HbA1c (panels E and F).
Each panel illustrates individual values with closed circles. In the panels D and E, the linear regression lines are expressed. Fibrous cap thickness is positively and linearly correlated with HDL-C (panel D, y = 23.4x+69.2, r = 0.248 and p = 0.039). Maximum lipid arc was positively and linearly correlated with HbA1c (panel E, y = 0.544x+58.3, r = 0.244, p = 0.039). In other panels, only r and p values of linear regression analysis were expressed because correlation was not statistically significant.