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Fig 1.

Cumulative antibiotic release amount in high dose group.

Graphs showing cumulative antibiotic released from cement specimens of (A) Simplex P; (B) Osteobond; (C) PALACOS R; and (D) CMW loaded with high (4g vancomycin) dose preparations of Sterile Vancomycin, Lyo-Vancin or Vanco in broth elution assay for 336 hours. Values are shown as the mean and standard error of the mean for eight specimens in each group.

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Fig 1 Expand

Fig 2.

Cumulative antibiotic release amount in low dose group.

Graphs showing cumulative antibiotic released from cement specimens of (A) Simplex P; (B) Osteobond; (C) PALACOS R; and (D) CMW loaded with low (1g vancomycin) dose preparations of Sterile Vancomycin, Lyo-Vancin, or Vanco in broth elution assay for 336 hours. Values are shown as the mean and standard error of the mean for eight specimens in each group.

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Fig 2 Expand

Fig 3.

Ultimate compressive strength in high dose group.

Mean ultimate compressive strength of (A) Simplex P; (B) Osteobond; (C) PALACOS R; and (D) CMW cement samples loaded with high (4g vancomycin) dose preparations of the 3 brands of antibiotics before and after 336-hour broth elution assay relative to cement without antibiotics (control). Values are shown as the mean and standard error for each group.

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Fig 3 Expand

Fig 4.

Ultimate compressive strength in low dose group.

Mean ultimate compressive strength of (A) Simplex P; (B) Osteobond; (C) PALACOS R; and (D) CMW cement samples loaded with low (1g vancomycin) dose preparations of 3 brands of antibiotics before and after 336-hour broth elution assay relative to cement without antibiotics (control). Values are shown as the mean and standard error for each group.

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Fig 4 Expand