Table 1.
Effect of the inhibition of Gal-3 on general and renal parameters in HFD rats.
Fig 1.
Effects of pharmacological inhibition of Gal-3 on renal damage in obese rats.
Expression of mRNA of Gal-3 (A). Quantification of fibrotic markers expression (B). Representative microphotographs of renal sections stained with Sirius red (C). Quantification of tubulointerstitial fibrosis (D). Expression of epithelial-mesenchymal transition molecules (E). Expression of inflammatory mediators (F). Expression of kidney damage markers (G). Magnification of the microphotographs 40x. Histogram bars represent the mean ± SEM of each group of animals (n ≥ 7 per group) in arbitrary units or as a percentage of staining normalized to HPRT and β-actin for cDNA. *p<0.05 vs. control group; $p<0.05 vs HFD group.
Table 2.
Effect of the inhibition of Gal-3 on general and renal parameters in AS rats.
Fig 2.
Effects of pharmacological inhibition of Gal-3 on renal damage in AS rats.
Expression of Gal-3 (A). Quantification of fibrotic markers expression (B). Representative microphotographs of renal sections stained with Sirius red (C). Quantification of tubulointerstitial fibrosis (D). Expression of epithelial-mesenchymal transition molecules (E). Expression of inflammatory mediators (F). Expression of kidney damage markers (G). Magnification of the microphotographs 40x. Histogram bars represent the mean ± SEM of each group of animals (n ≥ 7 per group) in arbitrary units or as a percentage of staining normalized to HPRT and β-actin for cDNA. *p<0.05 vs. control group; $p<0.05 vs AS group.