Table 1.
Eligibility criteria used for literature search and screening.
Table 2.
Categories of types of diets pre-specified in the survey.
Fig 1.
Flow chart of screening process according to PRISMA.
[23]
Table 3.
Characteristics of included studies–trials modifying fatty acid intake by supplementation.
Table 4.
Characteristics of included studies–trials modifying Vitamin D intake by supplementation.
Fig 2.
Overall risk of bias across all included studies as judged by the reviewers.
Note: `Other sources of bias`are relevant in certain circumstances, relating mainly to particular trial designs (e.g. carry-over in cross-over trials and recruitment bias in cluster-randomized trials). [14].
Fig 3.
Risk of bias of included studies as judged by the reviewers.
Note: `Other sources of bias`are relevant only in certain circumstances, relating mainly to particular trial designs (e.g. carry-over in cross-over trials and recruitment bias in cluster-randomized trials). [14].
Table 5.
Sociodemographic data of PwMS and controls.
Fig 4.
Type of diet among PwMS and controls in % (n = 473).
* = significant difference (p<0.001) PwMS = Patients with MS.
Fig 5.
Patients’ goals of using specific diets.
(n = 143) (Multiple answers possible).
Fig 6.
Influence of different factors on disease course in the perception of PwMS.
Patients could attribute 0 to 100 points to the different factors, 0 meaning no influence, 100 meaning maximum influence. n = 337 DMD = Disease Modifying Drugs.
Fig 7.
Importance of different topics in a patient education program.
Percentage of PwMS assigning rank 1 or 2 to the topic (n = 113).
Table 6.
Content of the education program.
Table 7.
Pilot evaluation of the program by 11 PwMS; Median and Range (0–10) are displayed.