Table 1.
The characteristics of 139611 patients with resectable breast cancer.
ER: Estrogen receptor; HoR: Hormone receptor; PR: prognosis receptor; IDC: Infiltrating duct carcinoma; and MBC: mucinous breast cancer.
Fig 1.
The survival of patients with MBC and IDC by Kaplan-Meier analysis.
Patients with MBC obviously had better survival (HR = 0.26; 95% CI, 0.21–0.31, and P < 0.001) with 5- and 10-year CSS rates of 98.23% and 96.03% versus 91.44% and 85.48% in patients with IDC, respectively. IDC: infiltrative ductal cancer; MBC: mucinous breast cancer; and CSS: cancer specific survival.
Fig 2.
The forest plot of subgroup analysis.
Except for the well-differentiated type, T4-classification or N3-classification subgroup, patients with MBC had better outcomes than patients with IDC. IDC: infiltrative ductal cancer; MBC: mucinous breast cancer; HR: hazard risk; and CI: confidence index.
Fig 3.
Univariate analysis based on the competing risk regression model.
Factors of N-classification (3A), T-classification (3B), Race (3C) and HoR status (3D) were significant prognostic factors for survival.
Table 2.
The characteristics of 3042 patients with resectable mucinous breast cancer.
ER: Estrogen receptor; HoR: Hormone receptor; and PR: prognosis receptor.
Fig 4.
Stacked cumulative incidence plot of breast cancer-specific survival and non-breast cancer-specific survival.
Non-breast cancer specific survival had a predominant impact on the survival.
Fig 5.
Nomogram for predicting the CSS of patients with MBC.
The nomogram is used by summing the points identified on the top scale for each independent covariate. The total points projected to the bottom scale indicate the % probability of the 5-, 10-, and 15-year survival. Race: 1 = white, 2 = black and 3 = other; Marital status: 1 = married; 2 = single (never married or having a domestic partner) and 3 = divorced (separated, divorced, or widowed). Location: 1 = central portion of the breast, 2 = upper-inner quadrant of the breast, 3 = lower-inner quadrant of the breast, 4 = upper-outer quadrant of the breast and 5 = lower-outer quadrant of breast. T and N-classification according to the 7th AJCC TNM system. ER = estrogen receptor: 1 = positive and 0 = negative. PR = progesterone receptor: 1 = positive and 0 = negative. CSS: cancer specific survival and MBC: mucinous breast cancer.
Table 3.
Point assignment and prognostic score in the nomogram.
CSS: cancer specific survival.
Fig 6.
The calibration curve for predicting patient CSS rates at 5 and 10 years.
The nomogram-predicted probability of CSS is plotted on the x-axis; the actual CSS is plotted on the y-axis. CSS: cancer specific survival and MBC: mucinous breast cancer.