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Fig 1.

Study design.

* eligible individuals; ** Individuals who actually participated in the study; *** Individuals with a validated diagnosis of type 2 diabetes and who reported to have diabetes; Ɨ Due to new incident cases and dropout of prevalent cases the altogether 565 observations with type 2 diabetes stem from 375 different individuals: 64 only S4, 50 only F4, 106 only FF4, 48 S4 and F4, 69 F4 and FF4, 3 S4 and FF4, 35 S4, F4 and FF4.

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Fig 1 Expand

Table 1.

Characteristics of participants with type 2 diabetes.

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Table 1 Expand

Fig 2.

Time trends of patient self-management.

* Logistic regression model adjusted for sex, age, age2, education, diabetes duration, and history of CVD.

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Fig 2 Expand

Fig 3.

Time trends of physician delivered care.

* Logistic regression model adjusted for sex, age, age2, education, diabetes duration, and history of CVD.

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Fig 3 Expand

Fig 4.

Time trends of medication use.

* Logistic regression model adjusted for sex, age, age2, education, diabetes duration, and history of CVD.

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Fig 4 Expand

Fig 5.

Time trends of reaching treatment targets.

* Logistic regression model adjusted for sex, age, age2, education, diabetes duration, and history of CVD; ⊣ based on German guidelines 2014 [29]; ⌉ based on International guidelines 2014 [28].

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Fig 5 Expand

Table 2.

Time trends for intermediate outcomes and 10 year modeled cardiovascular risk.

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Table 2 Expand

Fig 6.

Time trends of microvascular complications.

* Logistic regression model adjusted for sex, age, age2, education, diabetes duration, and history of CVD.

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Fig 6 Expand

Table 3.

Time trends of health-related quality of life (HRQL) Ɨ.

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Table 3 Expand