Fig 1.
Flow chart of study populations.
Flow chart of the KORA and Heinz Nixdorf Recall study populations showing exclusion criteria in accordance with the ACC/AHA risk score.
Table 1.
Basic description of study populations after applying exclusion criteria according to the ACC/AHA risk score.
Table 2.
Overall overestimation by risk scores.
Fig 2.
Calibration plots of ACC/AHA risk score before (left side) and after (middle) recalibration and of ESC SCORE (right side). Part A shows calibration in the pooled sample of KORA and HNR. Part B shows calibration by cohort (KORA: filled circles, HNR: triangles). The solid line indicates perfect calibration of the risk score. Depicted are mean estimated risk versus mean observed frequency per decile of estimated risk with axes ranging from 0 to 0.5 (50%).
Fig 3.
ROC curves of ACC/AHA risk score before (left side) and after (middle) recalibration and of ESC SCORE (right side). Part A illustrates performance in the pooled sample of KORA and HNR, while part B shows performance separately for KORA (solid) and HNR (dashed). C = C-statistic [95% confidence interval].