Table 1.
Definition of the variables.
Table 2.
Characteristics of the data.
Table 3.
Mean values of financial variables for orphan and non-orphan drug companies.
Table 4.
The impact of orphan drug company status on company performance.
Fig 1.
Relation between the number of orphan drugs marketed and the performance of companies.
Calculated from predictions of the fitted pooled OLS regression, with NORPHAN as the explanatory variable of interest, and with all other covariates fixed to average values. Data are presented as the means and 95% confidence bounds (S4 Table).
Table 5.
Sensitivity analyses using the number of orphans drugs sold per year (NORPHAN), a non-variant orphan dummy (DORPHAN), and the proportion of orphan drug sales to total sales (SORPHAN).