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Fig 1.

Chemical structure of morin.

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Fig 1 Expand

Fig 2.

SEM micrograph of AMSNPs-MOR.

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Fig 2 Expand

Table 1.

Zeta potential values of NPs dispersed in aqueous solutions at different pH.

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Table 1 Expand

Fig 3.

FTIR spectra.

(A) MSNPs (blue), AMSNPs (black), AMSNPs-MOR (red) and morin (green) in the range of 3600–1300 cm-1 and (B) MSNPs (blue), AMSNPs (black), AMSNPs-MOR (red) and morin (green) in the range of 1299–600 cm-1.

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Fig 3 Expand

Fig 4.

Morin adsorption onto silica nanoparticles.

(A) Adsorbed amount of morin as a function of different initial amount of morin; linear fit of experimental data obtained using (B) Langmuir (C) Freundlich and (D) Temkin isotherm models at 25°C. Values are the mean of n = 3 (mean± SD).

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Fig 4 Expand

Table 2.

Adsorption isotherms parameters of morin onto AMSNPs.

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Table 2 Expand

Fig 5.

Adsorption kinetics of morin onto AMSNPs.

(A) Effect of contact time; (B) linear fit of experimental data obtained using pseudo-first order model, (C) pseudo-second order model and (D) intra-particle diffusion model. Values are the mean of n = 3 (mean± SD).

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Fig 5 Expand

Table 3.

Adsorption kinetics parameters of morin onto AMSNPs.

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Table 3 Expand

Fig 6.

Removal of adsorbed morin by benzalkonium chloride (BAC).

Values are the mean of n = 3 (mean± SD). ****p < 0.0001 vs. control, ####p < 0.0001 vs. 0.1% BAC at 25°C or 0.01% BAC at 80°C.

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Fig 6 Expand

Fig 7.

Stern–Volmer type plot for singlet oxygen deactivation by AMSNPs-MOR.

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Fig 7 Expand

Fig 8.

EPR spectra.

Control (DMPO + H2O2+glycerin 10%); (B) morin (DMPO + H2O2 + morin 0.11 mM/glycerin 10%); (C) AMSNPs (DMPO + H2O2 + NP 6800 mg L-1/glycerin 10%); (D) AMSNPs-MOR (DMPO + H2O2 + morin 0.11 mM/NP 6800 mg L-1 /glycerin 10%). In spectrum (A), the symbol (#) indicates the presence of DMPO-HO• adduct. The symbol (*) indicates the presence of the DMPO/glycerin adduct; and the arrow indicates the peak that was used for the analysis of each spectrum.

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Fig 8 Expand

Fig 9.

Antioxidant capacity against HO• radical.

Control (0 μM morin), AMSNPs (0 μM morin), morin solution suspended in 10% glycerin (MORIN) (36 μM morin), AMSNPs-MOR (18 μM and 36 μM). All the values are given as average ± SD, in three independent assays (*p < 0.05 vs. control; ****p < 0.0001 vs. control).

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Fig 9 Expand