Fig 1.
MNI-normalized images of group-averaged (N = 7) whole brain resting cerebral blood flow (ml/100g/min).
Each session displayed, session 1(S1), session 2 (S2), and session 3 (S3), was the average of runs 1 and 2. Axial slice numbers (Z) in MNI co-ordinates are displayed at the bottom.
Fig 2.
Voxel-wise whole brain average within-subject coefficient of variance (wsCV) maps calculated for absolute CBF (aCBF) and CBF normalized by grey matter CBF (rCBF).
(A) within-session aCBF, (B) between-session aCBF, (C) within-session rCBF, and (D) between-session rCBF. Histograms were generated from each wsCV map.
Table 1.
Mean (± standard deviation) voxel-wise within and between-session: (A) wsCV and (B) ICC value for aCBF and rCBF images in select ROIs.
Fig 3.
Voxel-wise whole brain intraclass correlation coefficient (ICC) maps calculated for absolute CBF (aCBF) and relative CBF (rCBF).
(A) within-session aCBF, (B) between-session aCBF, (C) within-session rCBF, and (D) between-session rCBF. Histograms were generated from each ICC map.
Fig 4.
Whole brain group averaged (N = 7) arterial transit time maps for session 1 (A), session 2 (B), and session 3 (C). Voxel-wise between-session (D) and between-subject (E) coefficient of variance maps.
Fig 5.
Representative sample of regional CBF changes associated with finger tapping overlaid on a T1-weighted MNI template brain.
Activation maps were generated for: (a) within-session aCBF images, (b) rest and task aCBF images separated by a week and (c) aCBF images separated by a month, (d) rCBF images separated by a week and (e) rCBF images separated by a month. Regions in colour represent voxels that survived the statistical threshold after correction for family wise error (p < .05, FWE).
Fig 6.
Between-session (A) precision and (B) Dice coefficients expressed as a percent of within-sessionDR value. Absolute CBF is shown in light grey bars and relative CBF is shown in dark grey.