Fig 1.
Timeline of experiment.
Fig 2.
GFR day 1- GFR measured by 51Cr-EDTA clearance. Error bars represents 95% CI.
Fig 3.
NGAL-excretion day 1- NGAL excretion rate in urine. Error bars represents 95% CI.
Fig 4.
Renal Blood Flow—RBF measured by MRI at baseline, after reperfusion and 14 days after I/R-I. Error bars represents 95% CI.
Table 1.
Tissue metabolic activity (BOLD) and edema (ADC) measured by MRI in the left and right kidneys from Danegaptide (D) and vehicle (V) treated animals on experimental Day 1 (baseline and after reperfusion) and Day 14, respectively.
Fig 5.
GFR day 2—GFR measured by 51CR-EDTA clearance. Error bars represents 95% CI.
Table 2.
The numbers are expressed as a mean for all animals in the group. In the top table, the Danegaptide treated and the vehicle animals are compared. In the bottom table, the left, injured kidney is compared to the right, contralateral kidney.
Fig 6.
Plasma Danegaptide concentration: Measured on day 1. Error bars represents 95% CI.