Table 1.
The clinicopathological characteristics of 64 EGCs from 55 patients diagnosed after H. pylori eradication.
Fig 1.
The possible link between gastric mucosal atrophy and early gastric cancer (EGC) after H. pylori eradication.
(a) Two typical types of EGC, in relation to the endoscopically assessed atrophic mucosa. In case A, a cancerous lesion was observed as the reddish area (white arrowhead) within the atrophic border (white dotted line). In case B, a cancerous lesion was observed as the reddish area (white dotted line) within the atrophic area. (b) The association between the endoscopically assessed atrophic mucosa and the locations of 64 EGC lesions. The black circle shows the EGCs located within atrophic area; the grey circle shows the EGCs located within atrophic border; the white circle shows the EGCs located outside the atrophic area; gre, greater curvature; less, lesser curvature; AW, anterior; PW posterior.
Fig 2.
The histological degrees of mononuclear cell infiltration, atrophy, and metaplasia in the corpus and adjacent (ADJ) mucosa in the EGC patients.
Each factor was scored from 0 (normal) to 3 (marked). The statistical analysis was performed using Student's t-test.
Fig 3.
The degree of endoscopic atrophy, histological degrees of mononuclear cell infiltration, atrophy, and metaplasia in the corpus and adjacent (ADJ) mucosa compared to the anatomical location of gastric cancer.
The statistical analysis was performed using Student's t-test. L, lower; M, middle; U, upper.
Fig 4.
The degree of endoscopic atrophy (a), histological degrees of mononuclear cell infiltration (b), atrophy (c), and metaplasia (d) in the corpus and adjacent mucosa compared to the period after H. pylori eradication.
The statistical analysis was performed using Student's t-test.
Fig 5.
The association between the reasons for H. pylori eradication and the post-eradication period.
Post ESD, patients who underwent eradication after ESD for the gastric cancer; GU, gastric ulcer; the statistical analysis was performed using the chi-squared test.
Fig 6.
The degree of endoscopic atrophy (a), histological degrees of mononuclear cell infiltration (b), atrophy (c), and metaplasia (d) in the adjacent mucosa (ADJ) compared to the reasons for H. pylori eradication.
Post ESD, patients who underwent eradication after ESD for gastric cancer; GU, gastric ulcer; the statistical analysis was performed using Student's t-test.