Fig 1.
Decision-tree model for drug-induced hypoglycemia in older type 2 diabetic adults.
Square indicates the decision node (choice of glucose-lowering therapy between metformin, sulfonylurea, dipeptidyl peptidase4 inhibitor, thiazolidinedione, glucagon-like peptide1 receptor agonist, and basal insulin); circles indicate chance nodes; triangles indicate terminal nodes.
Table 1.
Average parameter values for calculation of incidence rates of mild hypoglycemia.
Table 2.
Input parameters for the base-case model.
Table 3.
Incidence rates, costs and quality-adjusted life-years associated with drug-induced hypoglycemia by medication class.
Table 4.
Results of the cost-effectiveness analyses.