Fig 1.
Gray matter regions showing a positive correlation with MMSE score.
The statistical map is co-registered and superimposed on 3D-T1 (A) axial (MNI coordinates: z = -20 to z = +75) and (B) coronal slices (MNI coordinates: y = -42 to y = +12) (MNI T1 template available on MRICRON software). Results are showed with a significance of P<0.05 corrected for multiple comparisons (FWE-corrected). Colour bar indicates the t-score for the regression slopes (from blue colour [t = 3.5] to red colour [t = 7.5]).
Fig 2.
Gray matter regions showing a positive correlation with MMSE score (blue color) and SMMSE score (red color).
The statistical map is co-registered and superimposed on 3D-T1-weighted axial (MNI coordinates y = -8) and coronal slices (MNI coordinates z = -16) (MNI T1-weighted template available on MRICRON software). Results are showed with a significance of P<0.05 corrected for multiple comparisons (FWE-corrected).
Fig 3.
Correlation between the MMSE score and the regional gray matter volume (rGMV) in right (R) and left (L) amygdala according to participants’ diagnostic category.
Plots points indicate the quantification of the VBM signal sampled from the voxels of the right and left amygdala. In black: whole sample of participants; red: cognitively healthy participants; blue: participants with MCI; green: participants with AD. L, left in [x y z], MNI coordinates. Results are shown for P<0.05 corrected for multiple comparisons FWE corrected.
Table 1.
Detailed results of the VBM analysis: correlation of gray matter volume with MMSE score and SMMSE score.
Fig 4.
Correlation between the SMMSE score and the regional gray matter volume (rGMV) in right (R) and left (L) hippocampus according to participants’ diagnostic category.
Plots points indicate the quantification of the VBM signal sampled from the voxels of the right and left hippocampus. In black: whole sample of participants; red: cognitively healthy participants; blue: participants with MCI; green: participants with AD. L, left in [x y z], MNI coordinates. Results are shown for P<0.05 corrected for multiple comparisons FWE corrected.