Table 1.
Parameters of mpMRI.
Fig 1.
Example of PI-RADS scoring with version 1 and 2 in a patient with prostate cancer.
mpMRI of an 82-year-old man with elevated PSA of 8.2 μg/l. The dominant lesion is located in the apex of the prostate in the pz and measures 12 x 18 x 17 mm. According to PI-RADS v2, DWI is the leading sequence. As the lesion has high signal intensity on b1000 with corresponding strong ADC reduction of 0.5 10−3 mm2/s as well as a diameter >15 mm the lesion was scored PI-RADS 5, highly likely to be malignant. No other sequence is required for scoring according to PI-RADS v2. With PI-RADS v1 a score for each sequence needs to be determined. For this patient the following scores were assigned: T2 TSE PI-RADS 5, DWI PI-RADS 5, DCE PI-RADS 5. This results in in a PI-RADS sum of 15 and a global PI-RADS 5. In this patient the time need for PI-RADS scoring with v2 after inspection of all images was 9 seconds, while it was 59 seconds with v1. MRI-guided in-bore biopsy revealed Gleason 3+4 = 7 tumor.
Table 2.
Comparison of patient data and MRI parameters in patients with and without prostate cancer.
Table 3.
PI-RADS scores assigned according to v1.
Table 4.
PI-RADS scores assigned according to v2.
Fig 2.
Diagnostic accuracy of PI-RADS scoring with the two versions for experienced and unexperienced readers.
ROC-curves show diagnostic accuracy of PI-RADS scoring for an experienced (reader 1) and less experienced reader (reader 2) with PI-RADS version 1 (continuous line) and version 2 (dashed line). Points and triangles correspond to PI-RADS thresholds. Sensitivies and specificities as well as Youden-selected thresholds are given in Table 2.
Table 5.
Diagnostic accuracy of mpMRI PI-RADS scores version 1 and version 2.
Fig 3.
Diagnostic accuracy of PI-RADS scoring with the two versions for peripheral and transitional zone lesions.
ROC-curves depict diagnostic accuracy of PI-RADS scoring for peripheral and transitional zone lesions with PI-RADS version 1 (continuous line) and version 2 (dashed line). Points and triangles correspond to PI-RADS thresholds. Sensitivies and specificities as well as Youden-selected thresholds are given in Table 3.
Table 6.
Diagnostic accuracy of mpMRI PI-RADS scores version 1 and version 2 for peripheral and transition zone lesions.